Voluntarily participating in an experiment to find a vaccine for the deadly Emmanuel Virus that's devastating Africa, Catholic Priest Sang Hyun manages to become the sole survivor of the experiment due to a contaminated blood transfusion that also infected him with the vampire virus. Back in Korea, the blood cravings begin to manifest, leading Hyun to quench his thirst while volunteering at the hospital.
One day, while in the hospital, he meets a childhood friend whose wife, Tae Ju, is living miserably. Feeling sorry, Hyun shows kindness toward her, but their relationship starts to change when he is unable to stop his desire for her.
